Six Sigma Control Limits and a Few Applications

Integrating Design and Control with Six-Sigma for Bioprocessing Applications

With worldwide revenues in excess of $400 billion in 2003, it is not surprising that the pharmaceutical industry can justify the investment of up to $ 800 million in the development of a new drug [1, 2]. However, with the main focus being on reducing time-to-market, the industry commonly relies on poor operating practice with regards to production losses, with low sigmalevels in the range 2-3 b...

Six Sigma: concepts, tools, and applications

Purpose – To provide a sound discussion on the Six Sigma methodology and see how it fits in with other quality initiatives. Design/methodology/approach – A conceptual paper that takes at in-depth look at the origins, pros and cons of Six Sigma and how it relates to some of the other quality initiatives in industry. Findings – The immediate goal of Six Sigma is defect reduction. Reduced defects ...

Six Sigma: A Preamble

A New Fuzzy Method for Assessing Six Sigma Measures

Six-Sigma has some measures which measure performance characteristics related to a process. In most of the traditional methods, exact estimation is used to assess these measures and to utilize them in practice. In this paper, to estimate some of these measures, including Defects per Million Opportunities (DPMO), Defects per Opportunity (DPO), Defects per unit (DPU) and Yield, a new algorithm ba...

Six-sigma application in tire-manufacturing company: a case study

Globalization, advancement of technologies, and increment in the demand of the customer change the way of doing business in the companies. To overcome these barriers, the six-sigma define–measure–analyze–improve–control (DMAIC) method is most popular and useful. This method helps to trim down the wastes and generating the potential ways of improvement in the process as well as service industrie...